Pyke Mid Lane Runes Guide - Patch 15.4

Primary Runes (Domination):

• Keystone: Hail of Blades
• Sudden Impact
• Sixth Sense
• Ultimate Hunter

Secondary Runes (Resolve):

• Demolish
• Bone Plating

Current Performance:

• Win Rate: 45.8%
• Pick Rate: 65.1%
• Based on 384 matches

Strong Matchups:

• Mel (53.9% WR)
• Senna (53.2% WR)
• Karma (52.2% WR)
• LeBlanc (52.0% WR)
• Leona (51.6% WR)
• Zoe (51.0% WR)

Weak Matchups:

• Elise (43.2% WR)
• Taric (43.7% WR)
• Maokai (44.8% WR)
• Thresh (45.3% WR)
• Fiddlesticks (45.7% WR)
• Lulu (46.9% WR)

Best Duo Synergies:

• Ziggs (56.2% WR)
• Draven (53.2% WR)
• Jinx (51.3% WR)
• Miss Fortune (51.1% WR)
• Twitch (51.1% WR)
• Vayne (50.9% WR)

Essential Tips:

1. Push and roam when Ultimate (R) is available
2. Watch enemy Flash cooldowns before using Ultimate
3. Flank from the side during teamfights using Q
4. Focus on side lane assistance after getting core items

Combat Strategy:

• Track enemy cooldowns carefully
• Use Ultimate strategically, anticipating escape abilities
• Position for side flanks in teamfights
• Prioritize wave clear and roaming after core items

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