Pyke Mid is a strong pick with a 53.8% win rate in patch 15.4. Here's the optimal build and strategy guide.

Core Build:

• Core Items: Profane Hydra > Ionian Boots > Youmuu's Ghostblade > Edge of Night > Opportunity > Death's Dance
• Summoner Spells: Flash, Teleport
• Skill Order: Q > E > W

Optimal Runes:

• Primary: Hail of Blades, Sudden Impact, Grisly Mementos, Ultimate Hunter
• Secondary: Magical Footwear, Biscuit Delivery
• Shards: Adaptive Force x2, Health (adjust defense shard based on matchup)

Key Tips:

• Push waves and roam when Ultimate (R) is available
• Track enemy Flash cooldowns before using Ultimate
• Flank from sides with Q in teamfights
• Focus on picking off isolated targets

Strong Against:

• Mel (53.9% WR)
• Senna (53.3% WR)
• Karma (52.2% WR)
• LeBlanc (52.0% WR)
• Leona (51.6% WR)

Weak Against:

• Elise (43.2% WR)
• Taric (43.7% WR)
• Maokai (45.0% WR)
• Thresh (45.3% WR)
• Fiddlesticks (46.4% WR)

Best ADC Synergies:

• Ziggs (56.4% WR)
• Draven (53.2% WR)
• Jinx (51.4% WR)
• Twitch (51.2% WR)
• Miss Fortune (51.2% WR)

Alternative Build: A secondary build swaps Profane Hydra for Hubris as first item, followed by Ionian Boots and Opportunity, achieving a 51.8% win rate. Adjust your item build based on enemy team composition and game state.

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