
Comprehensive Twitch Guide: Combos, Builds & Pro Tips for Season 14
Matchups Overview
Twitch's weaknesses lie against champions like Nilah (42.1%), Hwei (46.6%), Corki (46.8%), Viktor (46.9%), Tristana (47.0%), and Seraphine (47.1%).
However, Twitch excels against Smolder (53.0%), Aphelios (52.8%), Jinx (51.8%), Zeri (51.6%), Sivir (51.5%), and Jhin (51.4%).
Best Duo Synergies:
- Camille (56.7%)
- Sylas (54.9%)
- Taric (54.7%)
- Braum (53.2%)
- Shen (53.0%)
- Lulu (52.7%)

Rat creature wielding green laser weapon
Essential Tips & Tricks
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Ultimate Positioning: Line up your Ultimate (R) with multiple enemies to maximize damage output.
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Early Game Safety: Play conservatively in the early game due to weak early power. Focus on farming until your first item completion.
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Trade Strategy: Prioritize extended trades over short ones to maximize your passive poison damage.
Core Gameplay Patterns
- Focus on scaling through safe farming
- Position carefully to maximize ultimate damage across multiple targets
- Use stealth mechanics to set up advantageous fights
- Capitalize on extended trades where your poison can stack effectively
The champion requires careful positioning and patience, but rewards skilled play with high damage output and team fight impact potential.