Cassiopeia Mid Guide: Best Builds & Counter Picks (53.8% WR)

By Marcus Chen

December 11, 2024 at 06:27 PM

Cassiopeia is a scaling mage that excels at sustained magical damage through her poison abilities and Twin Fang spam. Here's her optimal builds and strategies for Mid lane:

Core Build

  • Flash + Teleport
  • First items: Rod of Ages > Archangel's Staff
  • Core items: Rylai's Crystal Scepter, Liandry's Torment, Rabadon's Deathcap
  • Skill order: E > Q > W

Optimal Runes

  • Primary: Conqueror, Presence of Mind, Legend: Haste, Last Stand
  • Secondary: Manaflow Band, Transcendence
  • Shards: Adaptive Force, Adaptive Force, Health Scaling

Key Tips

  • Manage mana carefully in early trades
  • Only commit to trades after landing Q
  • Strong level 2 all-in potential with Q+E combo
  • Build tanky items first for survivability

Strong Against

  • Smolder (62.5% WR)
  • Corki (57.4% WR)
  • Swain (56.4% WR)
  • Yone (56.0% WR)
  • Yasuo (55.7% WR)

Weak Against

  • Vel'Koz (46.5% WR)
  • Syndra (46.6% WR)
  • Qiyana (46.7% WR)
  • Naafiri (46.8% WR)
  • Zoe (47.1% WR)

Best Synergies

  • Rammus (58

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