Neeko Mid Lane Optimal Runes Guide

Patch 14.24 Best Rune Setup (52.3% Win Rate):

Primary Tree - Sorcery:

• Keystone: Arcane Comet
• Manaflow Band
• Transcendence
• Scorch

Secondary Tree - Inspiration:

• Biscuit Delivery
• Cosmic Insight

Strong Against:

• Zoe (55.9% WR)
• Swain (54.7% WR)
• Alistar (54.4% WR)
• Blitzcrank (53.3% WR)
• Brand (53.0% WR)

Weak Against:

• Poppy (46.6% WR)
• Janna (46.8% WR)
• Zyra (47.2% WR)
• Sona (47.4% WR)
• LeBlanc (48.1% WR)

Best ADC Synergies:

• Nilah (59.2% WR)
• Kog'Maw (54.5% WR)
• Miss Fortune (53.9% WR)
• Seraphine (53.5% WR)
• Samira (53.0% WR)

Essential Tips:

1. Only transform when enemies haven't spotted you
2. Use W speed boost for Ultimate positioning
3. Maximize E root duration by hitting through multiple minions

Key Combos:

• E (root) → Q → Auto Attack
• W (clone) → R → E → Q
• Flash → R → E → Q (surprise engage)

These statistics are based on 7,813 analyzed matches in the current patch.

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