Best Nautilus Mid Runes & Win Rates - Patch 15.3

Best Nautilus Mid Runes & Win Rates - Patch 15.3

By Marcus Chen

February 26, 2025 at 09:09 PM

Optimal Nautilus Mid Runes (Patch 15.3)

Primary: Resolve

  • Keystone: Aftershock
  • Shield Bash
  • Second Wind
  • Overgrowth

Secondary: Precision

  • Triumph
  • Legend: Haste

Current Performance: 47.0% win rate with 24.9% pick rate (based on 132 matches)

Strong Matchups:

  • Yuumi (54.0% WR)
  • Mel (54.0% WR)
  • Pantheon (53.2% WR)
  • Zilean (52.7% WR)
  • Lux (52.5% WR)
  • LeBlanc (52.4% WR)

Weak Matchups:

  • Taric (37.1% WR)
  • Renata Glasc (43.1% WR)
  • Rell (43.3% WR)
  • Tahm Kench (44.5% WR)
  • Bard (45.2% WR)
  • Maokai (45.8% WR)

Best Duo Synergies:

  • Samira (52.3% WR)
  • Swain (52.2% WR)
  • Yasuo (51.7% WR)
  • Miss Fortune (50.9% WR)
  • Nilah (50.9% WR)
  • Sivir (50.9% WR)

This rune setup maximizes Nautilus's tankiness while providing crucial cooldown reduction through Legend: Haste. Aftershock synergizes well with his engage-heavy playstyle, while Shield Bash amplifies his passive shield. Second Wind helps with lane sustainability, and Overgrowth increases his health scaling. Triumph helps secure kills and survive teamfights.

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