In patch 15.4, Kalista performs best with Precision primary and Domination secondary runes, achieving a 48.1% win rate across 16,700 matches.

Best Rune Setup:

• Primary (Precision): Lethal Tempo, Triumph, Legend: Alacrity, Cut Down
• Secondary (Domination): Sudden Impact, Treasure Hunter

Strong Synergies:

• Senna (56.0% WR)
• Taric (53.5% WR)
• Thresh (51.6% WR)
• Janna (51.0% WR)
• Swain (51.0% WR)

Best Matchups:

• Mel (55.8% WR)
• Zeri (52.2% WR)
• Varus (51.7% WR)
• Jhin (50.7% WR)
• Kai'Sa (50.5% WR)

Weak Against:

• Swain (41.5% WR)
• Miss Fortune (41.7% WR)
• Smolder (42.7% WR)
• Aphelios (43.8% WR)
• Corki (44.3% WR)

Essential Tips:

1. Use Ultimate (R) for engagement or saving your Support
2. Hold Rend (E) until skirmish completion to maximize stack damage
3. Scout river with Sentinel (W) for maximum vision coverage

This data-driven setup optimizes Kalista's performance in the current meta, focusing on attack speed and early game dominance through precise rune selection and strategic matchup awareness.

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