Guardian is the optimal keystone rune for Braum support, achieving a 51.7% win rate in patch 14.23 based on 116,243 matches. Here's the most effective rune setup:

Primary (Resolve):

• Guardian
• Font of Life
• Second Wind
• Overgrowth

Secondary (Inspiration):

• Biscuit Delivery
• Cosmic Insight

Strong Matchups (54%+ Win Rate):

• Yuumi (55.2%)
• Blitzcrank (54.9%)
• Sylas (54.8%)
• Nautilus (54.6%)
• Pantheon (54.2%)

Weak Matchups (Below 50%):

• Taric (47.0%)
• Vel'Koz (47.1%)
• Senna (47.6%)
• Sona (49.0%)
• Brand (49.1%)

Best ADC Synergies:

• Seraphine (56.3%)
• Swain (56.1%)
• Kog'Maw (54.5%)
• Nilah (54.0%)
• Xayah (53.6%)

Key Tips:

1. Play reactively rather than aggressively - counter-engage when enemies initiate
2. Stay close to your ADC to maximize protection with your E (Unbreakable)
3. Conserve your E for extended trades and important engagements
4. Maintain mana efficiency by avoiding unnecessary ability usage in small trades
5. Position strategically to protect priority targets during teamfights

This defensive rune setup maximizes Braum's protective capabilities while providing necessary sustain through Biscuit Delivery and ability haste via Cosmic Insight.

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