Precision / Inspiration runes offer the highest success rate for Lee Sin Mid, boasting a 54.5% win rate across 112 matches in patch 15.4.

Primary Runes (Precision):

• Conqueror
• Triumph
• Legend: Alacrity
• Last Stand

Secondary Runes (Inspiration):

• Magical Footwear
• Cosmic Insight

Strong Against:

• Zed (55.0%)
• Nidalee (53.9%)
• Kha'Zix (53.1%)
• Gragas (52.3%)
• Rammus (52.1%)
• Jarvan IV (52.0%)

Weak Against:

• Darius (43.5%)
• Taliyah (44.7%)
• Gwen (45.3%)
• Skarner (45.3%)
• Rek'Sai (46.5%)
• Bel'Veth (46.7%)

Best Synergies:

• Annie (54.6%)
• Kled (53.7%)
• Kassadin (53.6%)
• Anivia (53.6%)
• Akshan (53.5%)
• Swain (53.3%)

Key Tips:

1. Don't feel obligated to follow every Q you land
2. Utilize Flash + Ultimate combo to kick priority targets into your team
3. Maintain wave control near your side for better trading opportunities

These statistics and recommendations are based on current patch data and high-level gameplay analysis.

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