Caitlyn's optimal runes combine Precision and Sorcery trees to maximize her poke and late-game scaling potential.

Primary Runes (Precision):

• Keystone: Fleet Footwork (49.1% win rate)
• Presence of Mind
• Legend: Bloodline
• Cut Down

Secondary Runes (Sorcery):

• Absolute Focus
• Gathering Storm

Strong Against:

• Kai'Sa (51.9% WR)
• Twitch (51.8% WR)
• Kalista (51.6% WR)
• Zeri (51.6% WR)
• Aphelios (51.4% WR)
• Vayne (50.9% WR)

Weak Against:

• Lux (43.8% WR)
• Seraphine (45.3% WR)
• Brand (45.5% WR)
• Veigar (45.6% WR)
• Hwei (45.7% WR)
• Ziggs (46.1% WR)

Best Support Synergies:

• Elise (54.6% WR)
• Vex (53.7% WR)
• Kennen (52.2% WR)
• Bard (52.0% WR)
• Taric (51.9% WR)
• Tahm Kench (51.6% WR)

Key Tips:

1. Utilize your superior auto-attack range to harass enemies when they last hit
2. Place traps (W) behind towers during sieges to zone enemies
3. Conserve your 90 Caliber Net (E) as an escape tool and maintain sufficient mana for emergencies

*Stats based on 234,411 matches in Patch 14.23

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