Kai'Sa Top Lane Runes Guide - Patch 15.4

Primary Runes (Precision):

• Lethal Tempo (Keystone)
• Triumph
• Legend: Alacrity
• Cut Down

Secondary Runes (Inspiration):

• Magical Footwear
• Biscuit Delivery

Current Performance:

• Win Rate: 43.2%
• Pick Rate: 51.2%
• Sample Size: 384 matches

Strong Against:

• Mel (54.3% WR)
• Ziggs (51.2% WR)
• Jhin (51.1% WR)
• Lucian (50.7% WR)
• Ezreal (50.6% WR)
• Kalista (49.9% WR)

Weak Against:

• Kog'Maw (42.3% WR)
• Nilah (43.7% WR)
• Aphelios (44.1% WR)
• Vayne (45.5% WR)
• Jinx (46.0% WR)
• Yasuo (46.3% WR)

Best Support Synergies:

• Sona (52.6% WR)
• Vel'Koz (52.0% WR)
• Amumu (51.9% WR)
• LeBlanc (51.6% WR)
• Poppy (51.4% WR)
• Zoe (51.0% WR)

This rune setup maximizes Kai'Sa's attack speed and sustain potential in the top lane while providing additional gold value through Magical Footwear and lane sustain with Biscuit Delivery. The combination of Lethal Tempo with Legend: Alacrity significantly enhances her early game trading potential and late-game scaling.

For optimal results, pair these runes with builds that emphasize her ability upgrades (Q, W, E) and adapt your itemization based on the enemy team composition.

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