Precision / Inspiration - Kai'Sa Runes Guide

Current win rate: 48.3% | Pick rate: 74.9% (Based on 170,236 matches)

Best Rune Setup in Patch 15.3:

• Primary Tree (Precision):

  • Keystone: Lethal Tempo
  • Triumph
  • Legend: Alacrity
  • Cut Down

• Secondary Tree (Inspiration):

  • Magical Footwear
  • Biscuit Delivery

Strong Against:

• Mel (51.4% WR)
• Jhin (50.3% WR)
• Ezreal (50.2% WR)
• Lucian (49.6% WR)
• Smolder (49.3% WR)
• Ashe (49.1% WR)

Weak Against:

• Nilah (42.6% WR)
• Kog'Maw (42.9% WR)
• Swain (43.9% WR)
• Jinx (45.4% WR)
• Vayne (45.6% WR)
• Aphelios (46.0% WR)

Best Support Synergies:

• Fiddlesticks (53.0% WR)
• Amumu (52.4% WR)
• Braum (50.9% WR)
• Zoe (50.8% WR)
• Maokai (50.3% WR)
• Alistar (50.3% WR)

Key Tips for Success:

1. Build mixed damage items (AD, AP, and attack speed) to maximize evolved skill potential
2. Use Ultimate (R) strategically for repositioning and shield protection in teamfights
3. Target isolated enemies with Q for maximum damage output, avoiding minion interference

Champion Difficulty: Hard

Note: Win rates and statistics based on current patch data.

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