Optimal Pyke Support Runes - Patch 14.24

Best Rune Setup (49.3% Win Rate, 66.2% Pick Rate):

Primary Tree - Domination:

• Keystone: Hail of Blades
• Sudden Impact
• Eyeball Collection
• Relentless Hunter

Secondary Tree - Resolve:

• Bone Plating
• Unflinching

Counter Matchups: Strong Against:

• Zilean (53.4% WR)
• Swain (53.0% WR)
• Zyra (52.9% WR)
• Brand (52.9% WR)
• Karma (52.7% WR)
• Xerath (52.4% WR)

Weak Against:

• Maokai (45.7% WR)
• Poppy (47.0% WR)
• Sona (47.1% WR)
• Pantheon (47.6% WR)
• LeBlanc (48.0% WR)
• Nami (48.1% WR)

Best ADC Synergies:

• Xerath (59.9% WR)
• Cassiopeia (58.9% WR)
• Heimerdinger (57.6% WR)
• Karthus (56.9% WR)
• Veigar (55.7% WR)
• Swain (55.0% WR)

Pro Tips:

1. Track enemy Flash cooldowns before using Ultimate (R)
2. Wait for enemies to use mobility abilities before initiating with Hook (Q)
3. Prioritize roaming to help jungler and mid laner when possible

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