Talon Mid Runes Guide - Patch 14.24

Optimal Rune Setup (51.3% Win Rate, 54.8% Pick Rate)

Primary: Domination

• Keystone: Electrocute
• Sudden Impact
• Eyeball Collection
• Relentless Hunter

Secondary: Sorcery

• Nimbus Cloak
• Absolute Focus

Strong Against:

• Smolder (58.0% WR)
• Malzahar (56.0% WR)
• Aurelion Sol (53.2% WR)
• Azir (53.2% WR)
• Fizz (53.1% WR)
• Lux (52.5% WR)

Weak Against:

• Gragas (42.9% WR)
• Malphite (45.2% WR)
• Irelia (46.6% WR)
• Zoe (47.1% WR)
• Lissandra (47.2% WR)
• LeBlanc (47.5% WR)

Best Duo Synergies:

• Gwen (56.4% WR)
• Fiddlesticks (55.1% WR)
• Bel'Veth (55.0% WR)
• Brand (55.0% WR)
• Ivern (54.8% WR)
• Rammus (54.6% WR)

Key Tips:

1. Prioritize early first blood to snowball your lead
2. Flank during team fights to reach squishy targets
3. Look for solo picks on isolated enemies, especially when they're warding

Combat Tips:

• Use Ultimate (R) to initiate surprise attacks
• Focus on eliminating squishy targets
• Utilize terrain for unexpected engage angles

This build data is based on analysis of 35,178 matches in the current patch.

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