For Gnar in Mid Lane, the optimal rune setup combines Resolve (Primary) and Precision (Secondary) paths, achieving a 47.3% win rate with a 41.5% pick rate across 110 matches in patch 15.3.

Primary Runes (Resolve):

• Keystone: Grasp of the Undying
• Demolish
• Bone Plating
• Overgrowth

Secondary Runes (Precision):

• Triumph
• Legend: Alacrity

Strong Matchups:

• Trundle (58.0% WR)
• Volibear (57.3% WR)
• Dr. Mundo (56.7% WR)
• Sion (56.3% WR)
• Poppy (56.3% WR)
• Pantheon (55.2% WR)

Weak Matchups:

• Zac (42.2% WR)
• Maokai (44.1% WR)
• Karma (44.7% WR)
• Cassiopeia (44.7% WR)
• Quinn (45.0% WR)
• Vayne (45.2% WR)

Best Synergizing Champions:

• Fiddlesticks (57.9% WR)
• Volibear (57.7% WR)
• Bel'Veth (55.0% WR)
• Karthus (54.4% WR)
• Skarner (54.2% WR)
• Wukong (52.7% WR)

This rune setup maximizes Gnar's lane presence while providing late-game scaling potential through Precision secondary runes. The combination particularly excels in matchups against melee champions where Grasp can be consistently procced.

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