Best LoL Twitch Builds Guide: Runes, Items & Matchups

Best LoL Twitch Builds Guide: Runes, Items & Matchups

By Marcus Chen

March 16, 2025 at 10:19 AM

Twitch is an ADC champion who excels in extended trades and late-game teamfights. This comprehensive guide covers the most effective builds and strategies for Patch 15.5.

Most Popular Build (53.8% WR, 12,440 matches)

  • Summoner Spells: Flash, Barrier
  • Runes: Lethal Tempo, Triumph, Legend: Alacrity, Cut Down
  • Secondary: Axiom Arcanist, Gathering Storm
  • Shards: Attack Speed, Adaptive Force, Health
  • Core Items: Yun Tal Wildarrows → Berserker's Greaves → Infinity Edge
  • Full Build: Add Runaan's Hurricane → Lord Dominik's Regards → Bloodthirster
  • Skill Order: E > Q > W

Alternative Build Options:

  1. The Collector Build (53.4% WR)
  • Same runes and summoners
  • Core: The Collector → Berserker's Greaves → Runaan's Hurricane
  • Complete with Infinity Edge, Lord Dominik's, Bloodthirster
  1. Press the Attack Build (52.7% WR)
  • Keystone: Press the Attack (rest unchanged)
  • Same item build as Collector variation

Key Matchups: Strong Against:

  • Sivir (54.6% WR)
  • Jhin (53.6% WR)
  • Aphelios (53.2% WR)

Weak Against:

  • Yasuo (39.3% WR)
  • Seraphine (44.5% WR)
  • Nilah (45.0% WR)

Best Support Synergies:

  • Taric (54.1% WR)
  • Pantheon (53.9% WR)
  • Lulu (53.5% WR)

Pro Tips:

  • Play safe early game until first item completion
  • Maximize Ultimate damage by lining up multiple enemies
  • Prioritize extended trades to utilize passive poison
  • Adjust defensive rune shard based on lane opponent

Situational Items:

  • Guardian Angel vs heavy burst
  • Blade of the Ruined King vs health-stacking teams
  • Mortal Reminder vs healing-heavy compositions

This build data is sourced from Emerald+ ranked matches and updated for current patch.

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