Best Lissandra Top Runes - 51.1% Win Rate Build in Patch 15.5

Best Lissandra Top Runes - 51.1% Win Rate Build in Patch 15.5

By Marcus Chen

March 15, 2025 at 11:45 AM

Domination / Sorcery Runes for Lissandra Top Current Win Rate: 51.1% | Pick Rate: 40.1% (Based on 867 matches)

Primary Runes (Domination):

  • Keystone: Electrocute
  • Cheap Shot
  • Grisly Mementos
  • Ultimate Hunter

Secondary Runes (Sorcery):

  • Axiom Arcanist
  • Transcendence

Strong Against:

  • Mel (56.3% WR)
  • Akali (54.4% WR)
  • Kayle (54.2% WR)
  • Aurora (53.7% WR)
  • Yasuo (53.4% WR)
  • Galio (53.3% WR)

Weak Against:

  • Taliyah (43.9% WR)
  • Swain (44.4% WR)
  • Anivia (44.6% WR)
  • Annie (45.5% WR)
  • Cassiopeia (45.9% WR)
  • Cho'Gath (46.7% WR)

Best Jungle Synergies:

  • Master Yi (55.7% WR)
  • Rammus (55.1% WR)
  • Briar (54.8% WR)
  • Shyvana (54.8% WR)
  • Bel'Veth (53.7% WR)
  • Kindred (53.6% WR)

Pro Tips:

  1. Position your Q to simultaneously hit both minions and enemy champions
  2. Use E for flanking opportunities in team fights, ensuring team follow-up
  3. When behind, focus on peeling for your carries using R on enemy frontline

These runes and strategies are most effective for Lissandra in the top lane during patch 15.5.

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