Domination + Sorcery provides optimal runes for Kha'Zix jungle, with a 49.2% win rate across 10,487 matches in patch 15.3.

Primary Runes (Domination):

• Keystone: Dark Harvest
• Sudden Impact
• Grisly Mementos
• Treasure Hunter

Secondary Runes (Sorcery):

• Absolute Focus
• Gathering Storm

Strong Against:

• Shyvana (56.6% WR)
• Gwen (56.0% WR)
• Rammus (54.7% WR)
• Gragas (54.2% WR)
• Sejuani (53.4% WR)

Weak Against:

• Ivern (44.1% WR)
• Rengar (44.3% WR)
• Nunu & Willump (46.3% WR)
• Skarner (46.5% WR)
• Karthus (47.2% WR)

Best Duo Synergies:

• Teemo (56.0% WR)
• Gragas (56.0% WR)
• Warwick (54.9% WR)
• Gnar (54.7% WR)
• Kennen (54.6% WR)

Key Tips:

1. Excel in early game through aggressive skirmishing and ganking
2. Strong 1v1 duelist against isolated targets - use this for early jungle invades
3. Evolve abilities at levels 6, 11, and 16 - prioritize Q evolution first

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